I've been working on a visual make over for an application that my company has. Went from a kludgy dropdown menu based system to a main menu at the top, sub menu to the left type page. Pretty simple over all, using a few more graphics and icons and what not. Looked pretty good compared against the old version. And then the trouble began. I was asked to put in some google ads. Not a problem, want to generate some revenue from this thing, but once I started getting the ads to show up, I found that they started to make a visual mess of the layout.

My question to you is, do you design a layout with ads in mind, or do you try to show horn them in later like I'm doing?